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Hans Hoppeler |
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Biography:
1. Personal Data Date of birth: August 26, 1948 Place of birth: Zürich Nationality: Swiss Civil status: Married with Barbara Elisabeth Grünig Hoppeler
Children:
Hester Anouk, September 10, 1975
Address:
Hühnerbühlrain 40
Work position:
Co-Director, Institute of Anatomy
2. Chronological summary of academic activities 1954 - 1967 Primary school and high school in Zürich and Bern (Switzerland) 1967 - 1974 Medical studies and diploma as medical doctor at the University of Bern 1973 - 1974 Thesis: "The ultrastructure of the normal human skeletal muscle. A morphometric analysis on untrained men, women and well-trained orienteers" This study was carried out at the Department of Anatomy of the University of Bern (Prof. E.R. Weibel) and the Swiss Federal School of Physical Education in Magglingen (Dr. med. H. Howald). The thesis won a first price of the Swiss Federal School of Physical Education in 1974 1974 - 1977 Internship at the hospital of Burgdorf, Switzerland 1977 - 1980 Research assistant and tutor at the Department of Anatomy, Bern 1980 - 1981 Oberarzt, lecturer and head of the Electron Microscopy Station at the Department of Anatomy, Bern 1982 Honorary Research Fellow at the Department of Physiology, The Medical School, University of Birmingham (UK). The fellowship was funded by "Schweizerische Stiftung für Medizinisch-Biologische Stipendien" for a collaboration with Dr. O. Hudlicka on the "Relationship of oxygen consumption and quantitative morphology in isolated soleus and gracilis muscles of the cat" 1983 - 1988 Oberarzt and lecturer at the Department of Anatomy, Bern 1985 - Associate of Zoology of the Museum of Comparative Zoology, Harvard University, Cambridge, MA (USA) 1985 Theodor Kocher-Price of the University of Bern for the work elucidating the quantitative relationships between the structural characteristics of skeletal muscle and its performance capacity 1986 Habilitation for Anatomy and Histology at the Faculty of Human Medicine of the University of Bern 1988 Price of the Swiss Society for Internal Medicine for the paper "Impact of physical training on the ultrastructure of midthigh muscle in normal subjects and in patients treated with glucocorticoids" (first co-author) 1988 - Promotion to tenured full professor responsible for the "Systematic Anatomy" unit at the Department of Human Anatomy of the University of Bern 1992 - 1994 Joint appointment between the Department of Anatomy, University of Bern and the Institute of Sports Sciences of the Swiss School for Sports, Magglingen 1995 - Abteilungsleiter, Functional Anatomy of the University of Bern 1996 Organizer of the “International Workshop on Muscle Research in Space” October 13-16, for the European Space Agency ESA cosponsered by CNES, CSA, DARA, NASA, NASDA 2004 - Co-Director, Institute of Anatomie
3. Research Activities 1971 - 1973 MD thesis at the University of Bern 1977 - 1982 Postdoctoral fellowship at the Department of Anatomy with the research group of Prof. E.R. Weibel. Subject: Application of stereological methods to the study of structure-function correlations in the respiratory system of skeletal muscle tissue. 1982 - 1983 Honorary Research Fellow at the Department of Physiology of the University of Birmingham (UK), to gain expertise for the application of physiological techniques to assess functional variables of muscle performance. 1983 - Independent research position for the study of structural aspects of energy metabolism in heart and skeletal muscle at the Department of Anatomy, Bern.
4. Teaching Activities 1977 - 1980 Tutor for histology and anatomy at the Department of Anatomy, Bern 1980 - Lecturer for histology and anatomy at the Department of Anatomy, Bern 1981 Elected as examiner for histology and anatomy by the Swiss Federal Office for Health 1979 - 1980 Lecturer and chairman of various morphometry workshops organized by Kontron, Germany 1986 Promotion to Privatdozent for Human Anatomy and Histology at the University of Bern 1988 - Responsible for teaching Systematic Anatomy; Macroscopy and Microscopy and Cell Biology to medical students. Responsible for 2-day-course of Sports Medicine for medical students 1993 - Overall responsibility for postgraduate teaching of Sports Medicine in Switzerland
5. Scientific Society Memberships 1978 - Freie Vereinigung der Anatomen an Schweizerischen Hochschulen Union Schweiz. Gesellschaften für Experimentelle Biologie (USGEB) 1979 - International Society for Stereology (ISS) 1985 - Member of the Swiss Federal Sport Science Committee (vice president) 1986 - 1994 Member of the International Committee for Equine Exercise Physiology 1991 - International Society for Mountain Medicine 1994 - Member of the American Physiological Society 1987 - 1997 Swiss Society for Sports Medicine; Executive Committee, Officer for postgraduate Education 1994 - 1997 Member of the European Society for Comparative Physiology and Biochemistry 1997 - Swiss Society for Sports Medicine (president) 1997 - 1998 Member of the Swiss Federal Commission for the reform for medical studies 1999 - Member of the International Commission on Work and Exercise Physiology (IUPS) 2001 Commission for Interfacultary PhD studies (PIAF), President 2002 National Antidoping Agency, President 2002 Member of the LEOPOLDINA, Deutsche Akademie der Naturforscher
6. Editorial Duties 2004 - Editor in Chief: Journal of Experimental Biology 2003 – 2004 Acting Editor in Chief: Journal of Experimental Biology 1995 – 2003 Editor: Journal of Experimental Biology 1999 Editorial Board: Science & Sports 1987 - 1994 Editorial Board: Respiration Physiology 1990 - Editorial Board: International Journal of Sports Medicine 1990 - Editorial Board: Clinical Journal of Sports Medicine 1991 - Editorial Board: Arzt und Sport
Guestreviews for
: American Journal of Physiology 7. Grants (after 2000) 1998 - 2001 Schweizerischer Nationalfonds: The molecular basis of functional and structural plasticity of human skeletal muscle tissue. Zusammen mit R. Billeter. 243’000.- sFr. 1998 - 2001 Schweizerischer Nationalfonds: Multi-nuclear magnetic resonance spectroscopy (MRS) on a clinical whole-body MR-system: In vivo analysis of energy metabolism ad ordered biological structures. Zusammen mit Ch. Bösch. 204’300.- sFr. 1999 - 2001 Sportwissenschaftliches Institut der Eidgenössischen Sportschule Magglingen: Diätetische Beeinflussung der Wiederauffüllkinetik der intramyozellulären Lipid- und Kohlehydratspeicher bei Ausdauertrainierten resp. -untrainierten Probanden. 120’750.- sFr.
1999 - 2002
Projekt mit dem Scheizerischen Olympischen Verband und dem Schweizerischen
Skiverband: Auf der Höhe für Salt Lake City 2002. 2000 Investitionskredit Universität Bern: Beitrag zur Anschaffung eines Taqman. 105'000.- sFr. 2000 Forschungsausschuss der Eidgenössischen Sportkommission: Wissenschaftliche Auswertung und Berichterstattung über die "ALPHA-Studie" (Abhängigkeit von Leistungsvermögen, psychologischen Faktoren und Herzfrequenzregu-lation bei Ausdauersportlern). Zusammen mit R. Vogel. 63'910.- sFr. 2000 Orthopädische Universitätsklinik Balgrist: im Rahmen des NF-Gesuchs "Influence of passive tension on the recovery of degereative changes induced by tenotomy of the rotator cuff musculature in the sheep". Beitrag 10'000.- sFr. 2001 Orthopädische Universitätsklinik Balgrist: im Rahmen des NF-Gesuchs "Influence of passive tension on the recovery of degereative changes induced by tenotomy of the rotator cuff musculature in the sheep". Beitrag 10'000.- sFr. 2001 - 2004 Schweizerischer Nationalfonds: Skeletal muscle plasticity: the contribution of the transcriptome to adaptations induced by mechanical activity and hypoxia. Zusammen mit M. Flück, C. Boesch und M. Vogt. 260'000.- sFr.
2001 - 2004
Schweizerischer
Nationalfonds:
Multi-nuclear magnetic resonance spectroscopy (MRS)
and imaging (MRI) on a clinical whole-body MR-system: Integrated,
non-invasive analysis of metabolism, microstructure, and function of human
skeletal muscle. Zusammen mit C. Boesch, R. Kreis, L. Tappy. 2001 - 2004 Forschungsausschuss der Eidgenössischen Sportkommission: Bestimmung der Höhensensitivität und deren Beeinflussbarkeit durch intermittierendes Oberkörper-Hypoxietraining bei Nordisch Kombinierern. Zusammen mit M. Vogt. 101’808.- sFr. 2002 Orthopädische Universitätsklinik Balgrist: im Rahmen des NF-Gesuchs "Influence of passive tension on the recovery of degereative changes induced by tenotomy of the rotator cuff musculature in the sheep". Beitrag 10'000.- sFr. 2002 Josephine Clark Fonds: Northern Blot. Zusammen mit M. Flück. 3'151.- sFr. 2002 – 2004 Schweizerischer Nationalfonds:Botulinum toxin enhanced muscular immobilization in difficult muscle-tenon-bone unit repair - an experimental study. Zusammen mit U. Munzinger, T. Stähelin, E. 131'300.- sFr. 2003 Fondation pour la Recherche Médicale: Adaptations moléculaire du phénotype musculaire squelettique suite à un entraînement en excentrique chez le patient insuffisant cardiaque. Stage post-doctoral à l’étranger, Joffrey Zoll, Strasbourg, (27’600Euro) 41'400 sFr. 2004 Forschungsausschuss der Eidgenössischen Sportkommission: Leistungsfähigkeit bei Eu- bzw. Hyperglykämie. Zusammen mit P. Diem. 37'800.- sFr. 2004 Forschungsausschuss der Eidgenössischen Sportkommission: Molekulare Schutzmechanismen bei Muskelkater. (M. Flück) 41'500.- sFr. 2004 IOC, Beitrag zur Durchführung eines Sportmedizinischen Kurses „Endurance Performance Testing and Interpretation“, 13.-17. Juni, Massa Marittima, Italy. 15'000.- sFr. 2004 - 2007 Schweizerischer Nationalfonds: "Multi-nuclear magnetic resonance spectroscopy (MRS) and imaging (MRI) on a clinical whole-body MR-system: non-invasive observation of metabolism in healthy and diabetic skeletal muscle and liver tissue" Zusammen mit Ch. Boesch. 296’000.- sFr. 2004 - 2007 Schweizerischer Nationalfonds: "Chronic eccentric exercise in frail elderly” Zusammen mit W. Perrig und K. Lippuner. 223'692.- sFr.
8. Selected last five publications Däpp Ch, Schmutz S, Hoppeler H, Flück M (2004) Transcriptional reprogramming and ultrastructure during atrophy and recovery of mouse soleus muscle. Physiological Genomics 20:97-107
Gelfi C, DePalma S, Rimaponti M, Eberini I, Wait R, Bajracharya A, Marconi C, Schneider A, Hoppeler H, Cerretelli P (2004) New aspects of altitude adaptation in Tibetans: a proteomic approach. Faseb J. 18(3):612-614
Gerber C, Meyer DC Schneeberger AG, Hoppeler H, Von Rechenberg B (2004) Effect of tendon release and delayed repair on the structure of the involved muscles of the rotator cuff. An experimental study in sheep. J Bone Joint Surg Am 89-A(9):1973-1982
Meyer DC, Hoppeler H, von Rechenberg B, Gerber C (2004) A pathomechanical concept explains the muscle loss and fatty muscular changes following surgical tendon release. J Orthopaed Res 22:1004-1007
Weibel ER, Bacigalupe L, Schmitt B, Hoppeler H (2004) Allometric scaling of maximal metabolic rate in mammals: Muscle aerobic capacity as determinant factor. Respir Physiol Neurobiol 140:115-132
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