Research Interests:
· Differential gene expression in prokaryotes and eukaryotes.
· Study of gene regulation through transgenesis.
· Novel/recombinant gene expression in transgenic animal.
· Fish genetics.
PUBLICATIONS:
Chapters in Books
1) Rahman, M.A. and Maclean, N. (1998) Production of lines of
growth enhanced transgenic tilapia (Oreochromis niloticus) expressing
a novel piscine growth hormone gene. In: New Developments in Marine
Biotechnology (Y. Le Gal and H.O. Halvorson, eds.) Plenum Press, New
York, USA : 19-28.
2) Maclean, N and Rahman A. (1994). Transgenic Fish. In Animal
with novel genes (N. Maclean ed.), Cambridge Univ. Press. USA. :61-105
Journals
3) Sanden, M., Bruce, I. J., Rahman, M. A. and Hemre, G.-I. (2004)
The fate of transgenic sequences present in genetically modified (GM)
plant products in fish feed, investigating the survival of GM soybean
fragments during feeding trials in Atlantic salmon Salmo salar L. Aquaculture
(In Press).
4) Hwang, G., Muller, F., Rahman, M. A., Williams, D. W., Murdock,
P. J., Pasi, K. J., Goldspink, G., Farahmand, H. and Maclean, N. (2004).
Expression of Human Coagulation Factor VII in Fish Embryos by Gene Transfer.
Marine Biotechnology. Online first
5) Maclean, N. Hwang, G., Molina, A., Ashton, T., Muller, M., Rahman,
M. A. and Iyengar, A. (2003). Reversibly-Sterile Fish Via Transgenesis.
ISB News Report (December, 2003), Virginia Tech, Blacsburg, VA 24061.
6) Farahmand, H., Rahman, M.A., Sohm, F., Hwang, G-L., Maclean,
N. (2003) Isolation and expression of Tilapia (Orechromis niloticus)
serine 8 type GnRH coding and regulatory sequences. Gene, 304: 97-106.
7) Hwang, G-L., Rahman, M.A., Razak, S.A., Sohm, F., Farahmand,
H., Smith, A., Brooks,C., Maclean, N. (2003) Isolation and characterisation
of tilapia ß-actin promoter and comparison of its activity with
carp ß-actin promoter. Biochimica et Biophysica Acta, 1625 (1):
11-18
8) Maclean, N., Rahman, M.A., Sohm, F., Hwang, G-L., Iyengar,
A., Ayad, H. Smith, A., Farahmand, H. (2002). Transgenic tilapia and
the tilapia genome. Gene, 295(2):265-277.
9) Rahman, M.A., Ronyai, A., Engidaw, B.Z., Juancey, K., Hwang,
G-L.,Smith, A., Roderick, E., Penman, D., Varadi, L. and Maclean, N.
(2001). Growth and nutritional trials on transgenic Nile tilapia containing
an exogenous growth hormone gene. Journal of Fish Biology. 59: 62-78
10) Rahman, M.A., Hwang, G-L., Razak, S.A., Sohm, F. and Maclean,
N. (2000). Copy number related transgene expression and mosaic somatic
expression in hemizygous and homozygous transgenic tilapia (Oreochromis
niloticus). Transgenic Research. 9: 417-427.
11) Razak, S.A., Hwang, G-L, Rahman, M.A. and Maclean, N. (1999).
Growth performance and gonadal development of growth enhanced transgenic
tilapia Oreochromis niloticus (L.) following heat-shock-induced triploidy.
Marine Biotechnology. 1: 533-544.
12) Rahman, M.A. and Maclean, N. (1999) Growth performance of
transgenic tilapia containing an exogenous piscine growth hormone gene.
Aquaculture 173: 333-346.
13) Maclean, N. and Rahman, M. A. (1998) Threefold growth enhancement
in genetically modified strains of tilapia fish. Proc. 6th World Congress
on Genetics Applied to Livestock Production, Armidale, Australia, 27:
100-103.
14) Rahman, M.A., Mak, R., Ayad, H., Smith, A. and Maclean, N.
(1998) Expression of novel piscine growth hormone gene results in enhancement
of growth in transgenic tilapia (Oreochromis niloticus). Transgenic
Research, 7:357-369.
15) Rahman, M.A. and Maclean, N. (1997) Growth enhanced transgenic
tilapia. In Proceeding of International symposium on tilapia in aquaculture
(K. Fitzsimmons ed.) Vol-2: 97-108
16) Rahman, M.A., Iyengar, A. and Maclean, N. (1997) Coinjection
strategy improves integration efficiency results in germline transmission
of a growth hormone gene in transgenic tilapia (Oreochromis niloticus).
Transgenic Research. 6: 369-377.
17) Alam, M.S., Lavendar, F.L., Iyengar, A., Rahman, M.A., Ayad,
H.H., Lathe, R. Morely, S.D. and Maclean, N. (1996). Comparison of the
activity of carp and rat beta actin gene regulatory sequences in tilapia
and rainbow trout embryos. Molecular Reproduction and Developpment.
45:117-122.
18) Maclean, N., Iyengar,A., Rahman, A., Sulaiman, Z. and Penman,
D. (1993). Transgene transmission and expression in rainbow trout and
tilapia. Biology International 28: 95-97.
19) Rahman, A and Maclean N. (1992). Fish transgene expression
by direct injection into fish muscle. Molecular Marine Biology and Biotechnology.
1(4/5): 286-289.
20) Maclean, N., Iyengar, A., Rahman, A., Sulaiman, Z. and Penman,
D. (1992). Transgene transmission and expression in rainbow trout and
tilapia. Molecular Marine Biolgy and Biotechnology. 1(4/5): 355-365
21) Rahman, M.A. and Maclean, N. (1992). Introduction of novel
gene into tilapia (Oreochromis niloticus) by one-cell-stage injection.
Aquaculture. 105:219-232.
22) Penman, D.J., Iyengar, A., Beeching, A.J., Rahman, A., Sulaiman,
Z. and Maclean, N. (1991). Patterns of transgene inheritance in rainbow
trout (Oncorhynchus mykiss). Molecular Reproduction and Development.
30: 201-206.
23) Shah, M.S., Rahman, M.A., Deppertt, D. and Rab, M.A. (1990).
Seduced breeding of Indian major carps (L. rohita, C. mrigala and L.
calbasu). Asian Fisheries Science. 3: 257-262.
24) Rahman, M.A., Dewan, S., Rahmatullah, A.S.M and Das, N.N.
(1985). Experiment on induce breeding of indigenous major carps by pituitary
hormone injection. Bangladesh J. Aquaculture. 6-7:51-57.
25) Rahman, M.A., Shah, M. S., Deppert, D., Perschbaker, P. and
Khondokar, M. H. (1988). Guidelines in the operation of carp facilities
in Freshwater Aquaculture Research Station, Mymensingh, Bangladesh.
Final Report, Vol. VI DANIDA/FARS.
Nucleotide Sequence
26) GeneBank accession Number AF467291: Orechromis niloticus GnRH1 preprohormone
(GnRH) gene complete cds
Abstracts
27) Maclean, N., Razak, S. A.,and Rahman, M. A. (2000). Performance
of growth enhanced transgenic tilapia Oreochromis niloticus, following
heat-shock induced triploidy induction. In World Aquaculture Society
meeting, France.
28) Rahman, M. A., Mak, R., Ayad, H. and Maclean, N. (1997) Expression
of an exogenous piscine growth hormone gene results in enhanced growth
in transgenic tilapia (Oreochromis niloticus). In 4th International
Marine Biotechnology conference, Italy. p25.
29) Rahman, M. A., Smith, A., Mak R., Ayad, H. and Maclean, N.
(1997). Expression of an exogenous piscine growth hormone gene results
in enhanced growth in transgenic tilapia (Oreochromis niloticus). In
VI International symposium on Genetics in Aquaculture, Stirling, UK.
30) Rahman, M.A., Rowan, M. and Maclean, N (1994). Expression
and transmission of transgene in tilapia. In Experimental Biology meeting,
St. Andrews, Scotland, UK.
31) Penman, D. J., Iyengar, I., Beeching, A. J., Rahman, A.,
Sulaiman, Z., Bromage, N and Maclean, N. (1992). Inheritance of the
MTrGH gene in transgenic rainbow trout. Aquaculture 100 (1-3):102.
32) Rahman, M.A., Sulaiman, Z. and Maclean, N. (1991) Introduction
of novel genes into tilapia. In 2nd International Marine Biotechnology
Conference, Baltimore, USA
33) Shah, M. S., Rahman, M.A., Kibria, M. G. (1989). Induction
of triploid silver carp (Hypophthalmicthys molitrix) and test on their
growth performance. In 2nd Asian Science Forum, Tokyo, Japan, Abs. 136.
34) Shah, M.S., Rahman, M. A., Islam, M. S. and Choudhury, H.
A. (1989). Growth performance of triploid rohu (Labeo rohita) produced
by heat-shock treatment. In 2nd Asian Science Forum, Tokyo, Japan. Abs.
135.
35) Rahman, M.A., Haque, Z., Shah, M. S. and Deppert, D. (1998).
Large scale breeding of Indian Major carps and Chinese carps under varied
hormone dosage and interval routines in Bangladesh. In 19th Annual Conference
and Exposition, World Aquaculture Society. P63.