BIOINORGANIC CHEMISTRY
BIOINORGANICA
| A.Y. | Credits |
|---|---|
| 2016/2017 | 6 |
| Lecturer | Office hours for students | |
|---|---|---|
| Mauro Formica |
| Teaching in foreign languages |
|---|
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Course partially taught in a foreign language
English
This course is taught partially in Italian and partially in a foreign language. Study materials can be provided in the foreign language and the final exam can be taken in the foreign language. |
Assigned to the Degree Course
| Date | Time | Classroom / Location |
|---|
Learning Objectives
The course of Bioinorganic has the aim to provide students the main bases of bioinorganic chemistry. It takes into account the role of metal ions within the biologic systems. In the first part of the course the principles of the coordination chemistry will be discussed. Subsequently, the role of transition metal ions into some important biological and nutritional processes will be studied in detail.
Program
01 - Overview of Bioinorganic chemistry (1 hour)
02 - Principles of coordination chemistry related to Bioinorganic chemistry (14 hours)
03- Properties of biological Molecules (2 hours)
04 - Physical methods in Bioinorganic Chemistry (4 hours)
05 - Metal ions in biology (2 hours)
06 - Macroelements and microelements (2 hours)
07 - Mineral salts, uptake, lack and toxicity (2 hours)
08 - Control and utilization of metal-ion concentration in cells (2 hours)
09 - Metal ion folding and cross-linking of biomolecules (2 hours)
10 - Binding of metal ions and complexes to biomolecule-active centers (2 hours)
11 - Electron-transfer proteins (2 hours)
12 - Substrate binding and activation by nonredox mechanisms (2 hours)
13 - Atom- and group-transfer chemistry (2 hours)
14 - Metals in medicine (2 hours)
15 - Magnetic Resonance Imaging, radiodiagnostic agents, etc. (1 hour)
Bridging Courses
None
Learning Achievements (Dublin Descriptors)
The student must demonstrate to be able to:
- Draw and manage chemical formulas of coordination compounds
- Know metal/ligand selectivity in aqueous solution
- Use and compare thermodynamic stability constants
- Know the mechanisms of enzymatic catalysis
- Identify the role of the metal ion in metalloproteins
Teaching Material
The teaching material prepared by the lecturer in addition to recommended textbooks (such as for instance slides, lecture notes, exercises, bibliography) and communications from the lecturer specific to the course can be found inside the Moodle platform › blended.uniurb.it
Supporting Activities
Ppt files and scientific reviews published on international journals will be made available online (moodel platform)
Teaching, Attendance, Course Books and Assessment
- Teaching
The course will consist in lecturers
- Attendance
Mandatory
- Course books
1) "Principles of Bioinorganic Chemistry"; S.J. Lippard, J.M. Berg; University Science Books. 2) "Bioinorganic Chemistry"; I. Bertini, H.B. Gray, S.J. Lippard, J.S. Valentine; University Science Books.
- Assessment
Oral examination
- Disabilità e DSA
Le studentesse e gli studenti che hanno registrato la certificazione di disabilità o la certificazione di DSA presso l'Ufficio Inclusione e diritto allo studio, possono chiedere di utilizzare le mappe concettuali (per parole chiave) durante la prova di esame.
A tal fine, è necessario inviare le mappe, due settimane prima dell’appello di esame, alla o al docente del corso, che ne verificherà la coerenza con le indicazioni delle linee guida di ateneo e potrà chiederne la modifica.
Additional Information for Non-Attending Students
- Teaching
The program and teaching materials are the same for both attending and non attending students.
- Course books
1) Dispensa di Bioinorganica. 2) "Principles of Bioinorganic Chemistry"; S.J. Lippard, J.M. Berg; University Science Books. 3) "Bioinorganic Chemistry"; I. Bertini, H.B. Gray, S.J. Lippard, J.S. Valentine; University Science Books.
- Assessment
Oral examination
- Disabilità e DSA
Le studentesse e gli studenti che hanno registrato la certificazione di disabilità o la certificazione di DSA presso l'Ufficio Inclusione e diritto allo studio, possono chiedere di utilizzare le mappe concettuali (per parole chiave) durante la prova di esame.
A tal fine, è necessario inviare le mappe, due settimane prima dell’appello di esame, alla o al docente del corso, che ne verificherà la coerenza con le indicazioni delle linee guida di ateneo e potrà chiederne la modifica.
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