Università degli Studi di Urbino Carlo Bo / Portale Web di Ateneo


MOLECULAR MECHANISM OF METABOLIC DISEASES
MECCANISMI MOLECOLARI DELLE MALATTIE METABOLICHE

A.Y. Credits
2015/2016 6
Lecturer Email Office hours for students
Francesco Palma Thursday from 10 to 11 am, at Dipartimento Scienze Biomolecolari, via Saffi 2 (by email appointment)

Assigned to the Degree Course

Date Time Classroom / Location

Learning Objectives

The course will focus the study of the molecular mechanisms whose alterations are the basis of human metabolic diseases. The course will also address the molecular techniques of genome typing for both the diagnosis of genetic diseases and the assessment of the genetic predisposition to metabolic diseases will be considered.

Program

Topics.

  • Introduction: metabolism in humans.
  • Anatomy of the human genome.
  • Mutations that cause inherited metabolic diseases.
  • Genome typing.
  • The "snips" and the genetic susceptibility to metabolic diseases.
  • Regulation of gene expression and its alteration in the pathological states.
  • Signal-transduction pathways.
  • Inborn errors of metabolism.
  • Multifactorial metabolic disorders.
  • Metabolic syndrome and the lifestyle.
  • Teaching Material

    The teaching material prepared by the lecturer in addition to recommended textbooks (such as for instance slides, lecture notes, exercises, bibliography) and communications from the lecturer specific to the course can be found inside the Moodle platform › blended.uniurb.it

    Supporting Activities

    Slides of the lectures and notes in digital format.

    Self assessment tests


    Teaching, Attendance, Course Books and Assessment

    Course books

    Suggested books:
    DR Ferrier "Le basi della biochimica" 2015 Zanichelli;
    DL Nelson, MM Cox "Introduzione alla biochimica di Lehninger" 2015 Zanichelli.

    « back Last update: 12/05/2016

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