DRUG ANALYSIS I
ANALISI DEI FARMACI I
| A.Y. | Credits |
|---|---|
| 2016/2017 | 9 |
| Lecturer | Office hours for students | |
|---|---|---|
| Paola Bonifazi | Weekdays by appointment, except Saturdays |
Assigned to the Degree Course
| Date | Time | Classroom / Location |
|---|
Learning Objectives
The purpose of this course is to supply theoretical and practical mastery and competence, necessary for the basic operations in the qualitative and quantitative analysis of pharmaceuticals and toxic substances.
Program
Theoretical basis.
-Rules of security in the laboratories. Organisation. Equipments and instrumentation. Behavior.
-Basic techniques and operations: solubility, dilution, concentration; precipitation, settling, filtration, centrifugation, extraction.
-Analyses of inorganic ions of pharmaceutical and toxicological interest.
-Chromatographic techniques; notes concerning the separation mechanisms; adsorption, partition, exclusion, affinity, ion-exchange.
-Planar chromatography, paper chromatography, thin layer chromatography.
-Acid-base titrations in aqueous and non aqueous solutions; complexometric, red-ox and gravimetric titrations.
-Treatment of analytical data and application to the drug analysis.
Practical exercises.
-Separation and identification of cations and anions of pharmaceutical and toxicological interest. Analytical determinations by FU assays.
-TLC and HPTLC applications.
-Preparation of solutions and dilution.
-Quantitative analysis performed by titrations.
Bridging Courses
To take the exam of Analysis of Drugs I you must have passed the examination of General and Inorganica Chemistry and of Analytical Chemistry.
Learning Achievements (Dublin Descriptors)
Students must demonstrated that they have acquired mastery of thecniques applicable to the qualitative analysis of pharmaceutical substances and the quantitative analysis to determine the concentration of active ingredients in pharmaceutical products, applying classical and instrumental analysis methods.
Teaching Material
The teaching material prepared by the lecturer in addition to recommended textbooks (such as for instance slides, lecture notes, exercises, bibliography) and communications from the lecturer specific to the course can be found inside the Moodle platform › blended.uniurb.it
Teaching, Attendance, Course Books and Assessment
- Teaching
Oral lectures and laboratories.
- Attendance
The frequency of laboratory is compulsory.
- Course books
Reference books:
-P.Barbetti, M.G.Quaglia, L’analisi qualitativa nella chimica farmaceutica e tossicologica, Galeno Editore.
-G.C.Porretta, Analisi di preparazioni farmaceutiche. Analisi quantitativa, CISU Editore.
or
– E.Abignente, D.Melisi, M.G.Rimoli, Principi di Analisi Quantitativa dei medicinali, Ed. Loghìa.
In consultation:
-Farmacopea Ufficiale Italiana ed Europea.
-H.H.Bauer, G.D.Christian, J.E.O’Really, Analisi strumentale, Piccin Editore.
-L.F.Hamilton, S.G.Simpson, D.W.Ellis, Calcoli stechiometrici e problemi di chimica analitica, Piccin Editore.
- Assessment
Oral examination.
- Disabilità e DSA
Le studentesse e gli studenti che hanno registrato la certificazione di disabilità o la certificazione di DSA presso l'Ufficio Inclusione e diritto allo studio, possono chiedere di utilizzare le mappe concettuali (per parole chiave) durante la prova di esame.
A tal fine, è necessario inviare le mappe, due settimane prima dell’appello di esame, alla o al docente del corso, che ne verificherà la coerenza con le indicazioni delle linee guida di ateneo e potrà chiederne la modifica.
| « back | Last update: 26/08/2016 |
