Università degli Studi di Urbino Carlo Bo / Portale Web di Ateneo


A.Y. Credits
2020/2021 6
Lecturer Email Office hours for students
Mirco Fanelli please contact the lecturer
Teaching in foreign languages
Course partially taught in a foreign language English
This course is taught partially in Italian and partially in a foreign language. Study materials can be provided in the foreign language and the final exam can be taken in the foreign language.

Assigned to the Degree Course

Sanitary Nutritional and Environmental Biology (LM-6)
Date Time Classroom / Location
Date Time Classroom / Location

Learning Objectives

The objective of the Molecular Pathology and Laboratory course is to consider the pathology from a molecular point of view. Students will acquire informations concerning the altered molecular patterns - in different models of disease (focusing the neoplastic diseases) - with particular attention to epigenetics mechanisms  . Additionally, several experimental approaches will be considered to study the most relevant biological processes (e.g. apoptosis, gene expression, epigenetic profiles, etc.)


- The control of DNA stability: repair versus mutation

-       Cell death

-  Senescence, Telomeres and cancer stem cells

-  Experimental procedures for senescence/cell death indentification

-  Regulation of the gene expression: from transcription factors to  

  chromatin structure

-       Experimental approaches for gene expression studies

-       Methods for epigenetic studies

- Growth Factors Signaling and Oncogenes

- Growth inhibition and tumor suppressor genes

- Methods to study the cell cycle

-  The paradoxical model of APL: from the mechanism of the disease to therapy

Bridging Courses


Learning Achievements (Dublin Descriptors)

Knowledge and understanding - Acquisition of the tools to understand the molecular mechanisms of disease. Ability to use the language of their specific discipline.

Applying knowledge and understanding - Ability to recognize and apply the cognitive tools and the rigorous approach of the  Molecular Pathology as rational of any activity related directly and indirectly to health protection.

Indipendence of judgment - Being able to learn and independently evaluate the results of investigations on the pathogenesis and diagnosis of diseases

Communicative skills ?- Ability to explain, in a simple, immediate and exhaustive manner the acquired knowledge and to know how to interface with future professional roles (researchers, students, health-operative).

Learning ability - Upgrade capabilities through consultation of the scientific literatue of the discipline. Ability to participate, using the knowledge gained in the course, the continuous updating initiatives in the professional field.

Teaching Material

The teaching material prepared by the lecturer in addition to recommended textbooks (such as for instance slides, lecture notes, exercises, bibliography) and communications from the lecturer specific to the course can be found inside the Moodle platform › blended.uniurb.it

Supporting Activities

Lectures will be available online on the official site "blended learning" 

Didactics, Attendance, Course Books and Assessment





Course books

1) Stella Pelengaris and Michael Khan - THE MOLECULAR BIOLOGY OF CANCER - Second Edition

2) Robert A. Weinberg - THE BIOLOGY OF CANCER - Second Edition


Oral examination

Additional Information for Non-Attending Students





Course books

1) Stella Pelengaris and Michael Khan - THE MOLECULAR BIOLOGY OF CANCER - Second Edition

2) Robert A. Weinberg - THE BIOLOGY OF CANCER - Second Edition


Oral examination



« back Last update: 22/07/2020


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