Università degli Studi di Urbino Carlo Bo / Portale Web di Ateneo


CLINICAL PHARMACOLOGY
FARMACOLOGIA CLINICA

A.Y. Credits
2021/2022 6
Lecturer Email Office hours for students
Andrea Guidarelli Any working day (it is advisable to make an appointment by email at the address given, or by telephone at +39 0722 303524)
Teaching in foreign languages
Course with optional materials in a foreign language English Spanish
This course is entirely taught in Italian. Study materials can be provided in the foreign language and the final exam can be taken in the foreign language.

Assigned to the Degree Course

Biotecnologie mediche per la diagnostica e la terapia (LM-9)
Curriculum: BIOTECNOLOGIE PER LE TERAPIE INNOVATIVE
Date Time Classroom / Location
Date Time Classroom / Location

Learning Objectives

The aim of the course is to provide knowledge about routes of administration, metabolism, distribution, and elimination of biotechnological and synthetic drugs as well as the basic concepts of their therapeutic and the related toxic effects.

Program

Definition of drug (biotechnological and syntetic), medicine and poison.
Pharmacokinetics of biotechnological and synthetic drugs: Physicochemical factors in transfer of drugs across membranes, absorption, bioavailability, and routes of administration. Distribution of drugs. Biotransformation of drugs. Excretion of drugs.
Pharmacodynamics of biotechnological and synthetic drugs: Mechanisms of drug action, factors that modify the action of biotechnological and synthetic drugs (age, pathological states, drug interactions, tolerance) and the related toxic effects.

Bridging Courses

Knowledge of Molecular Biology and Physiology.

Learning Achievements (Dublin Descriptors)

At the end of the course the student possesses the basic knowledge of the mechanisms regulating the kinetics of biotechnological and synthetic drug in the body as well as interactions with the biological targets responsible for its activity. In particular, the student: - knows the essential elements of pharmacokinetics, - understands the basics of biotransformation, - knows how to interact with biological targets.

The topics discussed will then provide the student with basic knowledge of the relationships between biotechnological and synthetic drugs and molecular mechanisms of cellular metabolism. In addition, the major issues related to possible interactions between drugs.

Knowledge and understanding. At the end of the course, the student will have the skills to understand of the concepts of pharmacokinetics and pharmacodynamics and the notions relating to the molecular mechanisms underlying the action of biotechnological and synthetic drugs.

Ability to apply knowledge and understanding. At the end of the course, the student must be able to understand how the therapeutic response of biotechnological and synthetic drugs is conditioned by their pharmacokinetics and pharmacodynamics characteristics.

Judgment. At the end of the course, the student must be able to analyse and then predict therapeutic alternatives based on the pharmacokinetics pharmacodynamics parameters of biotechnological and synthetic drugs.

Communication skills. At the end of the course, the student must demonstrate that he/she is able to expose the notions referred in section knowledge and understanding through a scientific and critical lexicon.

Learning skills. At the end of the course, the student must demonstrate that he is able to independently know and learn the pharmacokinetics and pharmacodynamics of biotechnological and synthetic drugs that modulate the different pharmacological responses. Furthermore, will be able to build up his scientific knowledge in a critical way, using not only the study material provided by the professor but also dedicating himself to in-depth studies.

Teaching Material

The teaching material prepared by the lecturer in addition to recommended textbooks (such as for instance slides, lecture notes, exercises, bibliography) and communications from the lecturer specific to the course can be found inside the Moodle platform › blended.uniurb.it

Supporting Activities

Frontal lessons (MS Power Point).

The teaching material and the teacher's specific communications can be found, together with other support activities, within the Moodle platform> blended.uniurb.it


Teaching, Attendance, Course Books and Assessment

Teaching

Frontal lessons (MS Power Point).

Attendance

Knowledge of Molecular Biology and Physiology.

Course books

Farmaci biotecnologici - Aspetti farmacologici e clinici.  (Vegeto - Maggi - Minghetti). Casa Editrice Ambrosiana

Goodman and Gilman - Le basi farmacologiche della terapia (2019).

Assessment

The course is examined through oral examination with questions to evaluate the students' knowledge about the mechanisms of basic principles of pharmacology;  address the issues related to potential interactions between drugs, dietary supplements and food. The final mark (out of 30) will be based on the skill of the students to answer properly to the questions.

Additional Information for Non-Attending Students

Teaching

Non-attending students are encouraged to submit the Moodle teaching material (slide discussed in the lesson) through which you can deepen the study of the volumes indicated in the "Study texts" section.

Attendance

Knowledge of Molecular Biology and Physiology.

Course books

Farmaci biotecnologici - Aspetti farmacologici e clinici.  (Vegeto - Maggi - Minghetti). Casa Editrice Ambrosiana

Goodman and Gilman - Le basi farmacologiche della terapia (2019).

Assessment

The course is examined through oral examination with questions to evaluate the students' knowledge about the mechanisms of basic principles of pharmacology;  address the issues related to potential interactions between drugs, dietary supplements and food. The final mark (out of 30) will be based on the skill of the students to answer properly to the questions.

« back Last update: 23/07/2021

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