Università degli Studi di Urbino Carlo Bo / Portale Web di Ateneo


LABORATORY OF HEMATOLOGY AND IMMUNOLOGY
EMATOLOGIA ED IMMUNOLOGIA DI LABORATORIO

A.Y. Credits
2018/2019 6
Lecturer Email Office hours for students
Massimo Valentini
Teaching in foreign languages
Course with optional materials in a foreign language
This course is entirely taught in Italian. Study materials can be provided in the foreign language and the final exam can be taken in the foreign language.

Assigned to the Degree Course

Biological Sciences (L-13)
Curriculum: SANITARIO MOLECOLARE
Date Time Classroom / Location
Date Time Classroom / Location

Learning Objectives

The COURSE is structured and organized to provide students with basic, technological and application knowledge necessary to address the most common diagnostic strategies in HEMATOLOGY and IMMUNOLOGY LABORATORY , in addition to the elements necessary for a correct analysis and reporting of analytical results

Program

COURSE INTRODUCTION: TOPICS and OBJECTIVES

FUNCTIONAL ARCHITECTURE of the HAEMOLYMPHOPOIETIC SYSTEM

BLOOD: CHEMICAL, PHYSICAL AND BIOLOGICAL CHARACTERISTICS

BLOOD COLLECTION: OPERATING MODES and ERROR SOURCES

THE HEMOGRAM: MEANING OF THE MAIN ANALYTICAL PARAMETERS and REFERENCE INTERVALS

GUIDELINES on the HEMATOLOGICAL REPORT and INTERPRETATIVE COMMENTS

HAEMATOLOGICAL DIAGNOSTIC and AUTOMATION: TECHNOLOGIES and OPERATING PRINCIPLES

The MORPHOLOGY of the BLOOD CELLS and the HAEMOPOIETIC  CELL LINES

STAINING METHODS and MICROSCOPIC ANALYSIS of the PERIPHERAL BLOOD CELLS

MORPHOLOGICAL AND QUANTITATIVE ALTERATIONS of the ERYTROID CELL LINE (and related INSTRUMENTAL ALARMS)

MORPHOLOGICAL AND QUANTITATIVE ALTERATIONS of the MYELOID CELL LINE (and related INSTRUMENTAL ALARMS)

MORPHOLOGICAL and QUANTITATIVE ALTERATIONS of the LYMPHOID CELL LINE (and related INSTRUMENTAL ALARMS)

MORPHOLOGICAL AND QUANTITATIVE ALTERATIONS of the PLATELETS (and related INSTRUMENTAL ALARMS)

LABORATORY DIAGNOSTICS in ONCOHEMATOLOGY

The IMMUNOPHENOTYPICAL STUDY of BLOOD CELLS: REAGENTS and TECHNOLOGIES

FAB ,  WHO CLASSIFICATION and IMMUNOPHENOTYPIC CHARACTERIZATION of LEUKEMIA and LYMPHOMAS

LABORATORY DIAGNOSTICS and HEMOSTATIC BALANCE

SCREENING and 2nd LEVEL TESTS in the STUDY of HEMOSTASIS

LABORATORY DIAGNOSTICS in THROMBOFILIC RISK ASSESSMENT

LABORATORY TEST in TRANSFUSION MEDICINE: BLOOD GROUPS and COOMBS TEST

LABORATORY DIAGNOSTICS in AUTOIMMUNITY: ANALYTICAL PARAMETERS and TECHNOLOGIES

LABORATORY DIAGNOSTICS in the HLA SYSTEM ANTIGEN STUDY

QUALITY CONTROL: INTERNAL and EXTERNAL

ERRORS and STATISTICAL PARAMETERS in LABORATORY MEDICINE

Bridging Courses

CELL BIOLOGY, ANATOMY, PHYSIOLOGY

Learning Achievements (Dublin Descriptors)

NOWLEDGE AND UNDERSTANDING SKILLS: to pass the final interview / exam, the student will have to demonstrate the achievement of knowledge related to the physiopathology of the blood and lymphatic system, the main analytical and interpretive technologies and methodologies used in the diagnostic sectors of hematology and immunology.

D2- ABILITY TO APPLY KNOWLEDGE and UNDERSTANDING: the student will have to demonstrate his ability to use the knowledge and concepts learned during the course to address and solve the main diagnostic questions in the field of hematology and laboratory immunology

D3- AUTONOMY OF JUDGMENT: at the end of the course, the student must be able to independently assess which diagnostic algorithms are to be adopted in the various hematological and immunological analytical processes.

D4- COMMUNICATION SKILLS: at the end of the course the student must demonstrate that he has learned the elements of judgment necessary for the interpretation and reporting of the diagnostic investigations in the laboratory evaluation of the pathophysiology of the blood and lymphatic system.

D5- LEARNING SKILLS: the student must be able to discuss and interpret the results of the most common hematological and immunological investigations and propose the most appropriate choices for an optimal laboratory diagnostic path.

Teaching Material

The teaching material prepared by the lecturer in addition to recommended textbooks (such as for instance slides, lecture notes, exercises, bibliography) and communications from the lecturer specific to the course can be found inside the Moodle platform › blended.uniurb.it

Supporting Activities

The Professor declares himself available to hold, at the laboratory of the "OO RR Marche Nord" Hospital in Pesaro, short seminars for groups of students, aimed at understanding and learning the operational dynamics and technologies related to the diagnostic protocols in hematology and immunology


Didactics, Attendance, Course Books and Assessment

Didactics

LESSONS with the help of a video projector and slides of the various topics covered during the COURSE

Attendance

NONE

Course books

1. DACIE and LEWIS : PRACTICAL HAEMATOLOGY  Barbara J Bain, Imelda Bates, Mike A. Laffan  , 12th ed, 2016 ELSEVIER

2. MANUALE di EMATOLOGIA : Paolo Corradini, Robin Foà  2nd ed, 2015 MINERVA MEDICA

3. HOFFBRAND'S ESSENTIAL HAEMATOLOGY : A. Victor Hoffbrand ,  7th ed,  2015, WILEY - BLACKWELL

4. BLOOD  CELLS . A PRACTICAL GUIDE : Barbara J. Bain , 5th ed, 2015 ,  WILEY - BLACKWELL

5. Le BASI dell' IMMUNOLOGIA . FISIOPATOLOGIA del SISTEMA IMMUNITARIO :  Abul K. Abbas , Andrew K. Lichtman , Shiv Pillai , 5th ed , 2017, EDRA - MASSON

6. ROITT'S ESSENTIAL IMMUNOLOGY :  Dennis R. Burton, Ivan M. Roitt et al , 13th ed, 2017 ,  WILEY - BLACKWELL

7. IMMUNOLOGY and SEROLOGY in LABORATORY MEDICINE : Mary Louise Turgeon , 2013, MOSBY

8. le MALATTIE AUTOIMMUNI :  Corrado Betterle , 2nd ed, PICCIN

Assessment

The method of evaluating the notions learned during the Course involves a final interview, lasting 15 - 20 minutes, with the help of the slides published on the Moodle platform blended.uniurb.it, on three different topics covered during the Course. To pass the final exam, it is essential to answer sufficiently each of the three topics covered by the interview. For the assessment, the level of knowledge of the topics covered, the capacity and appropriateness of the exhibition, the links between the basic concepts of pathophysiology of the haemolymphopoietic system and related laboratory diagnostics will be considered, in accordance with what is indicated by the Dublin descriptors.
The assessment of the interview / exam is expressed in thirtieths (with a minimum score of 18).

Additional Information for Non-Attending Students

Didactics

All INFORMATIONS relating to this COURSE, addressed to ATTENDING students, is also valid for NON ATTENDING students

Attendance

TRAINING based on the TOPICS summarized in the COURSE PROGRAM, on the CONSULTATION of the indicated TEXTBOOKS and on the RELATED SLIDES.

Course books

1. DACIE and LEWIS : PRACTICAL HAEMATOLOGY  Barbara J Bain, Imelda Bates, Mike A. Laffan  , 12th ed, 2016 ELSEVIER

2. MANUALE di EMATOLOGIA : Paolo Corradini, Robin Foà  2nd ed, 2015 MINERVA MEDICA

3. HOFFBRAND'S ESSENTIAL HAEMATOLOGY : A. Victor Hoffbrand ,  7th ed,  2015, WILEY - BLACKWELL

4. BLOOD  CELLS . A PRACTICAL GUIDE : Barbara J. Bain , 5th ed, 2015 ,  WILEY - BLACKWELL

5. Le BASI dell' IMMUNOLOGIA . FISIOPATOLOGIA del SISTEMA IMMUNITARIO :  Abul K. Abbas , Andrew K. Lichtman , Shiv Pillai , 5th ed , 2017, EDRA - MASSON

6. ROITT'S ESSENTIAL IMMUNOLOGY :  Dennis R. Burton, Ivan M. Roitt et al , 13th ed, 2017 ,  WILEY - BLACKWELL

7. IMMUNOLOGY and SEROLOGY in LABORATORY MEDICINE : Mary Louise Turgeon , 2013, MOSBY

8. le MALATTIE AUTOIMMUNI :  Corrado Betterle , 2nd ed, PICCIN

Assessment

The method of assessment of the notions derived: from the COURSE PROGRAM, from the CONSULTATION of the TEXTBOOKS and from the SLIDES published on the BLENDED LEARNING PLATFORM, provides for a final interview, lasting 15 - 20 minutes, with the help of the slides of the LESSONS, on three different topics covered during the COURSE. To pass the final exam it is essential to answer sufficiently each of the three topics covered by the interview. For the assessment, the level of knowledge of the topics covered, the capacity and appropriateness of the exhibition, the links between the basic concepts of pathophysiology of thehaemoymphopoietic system and related laboratory diagnostics will be considered, in accordance with what is indicated by the Dublin descriptors.
The assessment of the interview / exam is expressed in thirtieths (with a minimum score of 18).

Notes

The Professor can be contacted by phone, EVERY DAY (9 am - 5 pm) at the "OO RR MARCHE NORD" HOSPITAL in PESARO ,  telephone numbers :

- +39  0721 - 362230

- +39  0721 - 365078

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