Università degli Studi di Urbino Carlo Bo / Portale Web di Ateneo


CLINICAL BIOCHEMICAL ANALYSES
ANALISI BIOCHIMICO-CLINICHE

A.Y. Credits
2025/2026 6
Lecturer Email Office hours for students
Daniela Ligi Monday-Friday by appointment via institutional email (daniela.ligi@uniurb.it) or phone (0722-304626)
Teaching in foreign languages
Course with optional materials in a foreign language English
This course is entirely taught in Italian. Study materials can be provided in the foreign language and the final exam can be taken in the foreign language.

Assigned to the Degree Course

Pharmacy (LM-13)
Curriculum: COMUNE
Date Time Classroom / Location
Date Time Classroom / Location

Learning Objectives

The course aims to provide the knowledge necessary for the interpretation of the main laboratory tests useful in the evaluation of the function of specific tissues, organs and systems, in order to apply this knowledge in the context of pathophysiological conditions related to major organs and systems.

Program

  • Preparation, handling, and storage of biological specimens of biomedical interest.
  • Quality of laboratory results: sources of variability, methods of evaluation and estimation of their clinical impact.
  • Main techniques in use in the clinical biochemistry laboratory, enzymatic determinations and their clinical use.
  • Tissue and organ clinical biochemistry.
  • Blood (CBC examination, electrophoretic profiling of serum proteins and its diagnostic significance, major plasma enzymes of diagnostic interest, markers of martial balance, morphological and pathogenetic classification of anemias, coagulation markers).
  • Urinalysis and renal function tests (Hints of nephron physiology, physical, chemical and microscopic examination of urine; renal function tests).
  • Hepatic diagnostics (Hints of physiology and anatomy, enzymes of diagnostic interest in hepatocellular diseases; bilirubin and jaundice, modification of serum proteins and coagulation factors in some hepatopathies).
  • Glucose metabolism diagnostics (introduction to hormones that regulate blood glucose, diagnostic criteria of diabetes mellitus, laboratory tests useful in the diagnosis and follow-up of the diabetic patient).
  • Lipid metabolism diagnostics (Lipoprotein classification and its metabolism, apolipoprotein classification, dyslipidemia and metabolic syndrome).
  • Cardiac diagnostics (Laboratory diagnosis of myocardial infarction).
  • Hints of endocrinological diagnostics.
  • Biomarkers of inflammation.
  • Biomarkers of nutritional status.
  • Clinical biochemistry analysis in Point Of Care Testing (POCT): legislative basis, POCT technologies, types of usable biological samples, main applications).
  • Bridging Courses

    As reported in the teaching regulations for the master's degree in Pharmacy, students are strongly advised to follow the sequence of the courses laid out in the study plan. Furthermore, in order to allow an adequate teaching and learning process, students have to pass the General and Molecular Biochemistry exam before taking the Clinical Biochemical Analyses exam.

    Learning Achievements (Dublin Descriptors)

    D1. Knowledge and Understanding: The student should show mastery appropriate to the professional profile of the Pharmacist of the basic knowledge related to the main metabolic pathways covered by clinical biochemistry tests, necessary for the identification and evaluation of the clinical utility of biomarkers, and understand the etiopathogenetic mechanisms of some pathological conditions. The student should also be familiar with the main biochemical methodologies applied in the laboratory medicine field in the measurement of biomarkers in pathophysiological conditions for diagnostic and prognostic purposes.
    D2. Applying knowledge and understanding: The student should be able to demonstrate his or her understanding of the concepts and theories covered in the course; therefore, he or she should be able to describe the main applications of clinical biochemical analyses and associate them with the appropriate diagnostic iter.

    D3. Making judgements: Students will have to demonstrate their ability to use knowledge and concepts that allow them to reason independently according to the specific logic of the discipline. In particular, Students must be able to use the skills acquired to analyze and critically evaluate proposed clinical questions and data, advancing hypotheses and seeking solutions, which include the advice of other health professionals. 

    D4. Communication skills: Students must demonstrate the ability to communicate their knowledge in a thorough, precise, and comprehensive manner to people already competent in the field of Clinical Biochemical Analyses, as well as demonstrate that they can summarize and simplify the topics in a popular way so as to be understandable even to those who are not experts in the sector, always adopting an adequate and precise terminology.

    D5. Learning skills: Students will have to demonstrate the ability to reach conclusions, examples, or parallels autonomously, on the basis of what they have learned from the program and on the basis of what they have learned using their own initiatives, by autonomously finding additional sources on biochemical analyses and on critical evaluation of laboratory biomarkers for diagnostic/prognostic purposes. Students will acquire the ability to interpret and autonomously judge the laboratory data, in order to apply the acquired knowledge in the practice of the profession.

    Teaching Material

    The teaching material prepared by the lecturer in addition to recommended textbooks (such as for instance slides, lecture notes, exercises, bibliography) and communications from the lecturer specific to the course can be found inside the Moodle platform › blended.uniurb.it

    Supporting Activities

    No supporting activities.


    Teaching, Attendance, Course Books and Assessment

    Teaching

    Frontal lessons.

    Innovative teaching methods

    Frontal lessons may be enriched with some innovative teaching methods, which will be proposed to the class and selected between the DEBATE or FLIPPED CLASSROOM forms based on the feedback from the students.

    Attendance

    Attendance of frontal lessons is strongly recommended.

    Course books

    Students may use one of the following texts of her/his choice:

    Biochimica Clinica e Medicina di Laboratorio. M. Ciaccio. Edises

    Medicina di Laboratorio - Logica e Patologia Clinica. Antonozzi - Gulletta - Piccin 2019 

    Biochimica Clinica Essenziale. Albi, Beccari, Cataldi. Zanichelli. 

    Assessment

    The assessment of the achievement of the course objectives (according to the Dublin descriptors) is based on an oral exam, carried out through at least 3 questions concerning the topics of the course to assess the knowledge, understanding of the scientific discipline, and ability to apply and coordinate the acquired knowledge.

    The evaluation is expressed in thirtieths (minimum mark 18/30, maximum mark 30/30 cum laude).

    Disability and Specific Learning Disorders (SLD)

    Students who have registered their disability certification or SLD certification with the Inclusion and Right to Study Office can request to use conceptual maps (for keywords) during exams.

    To this end, it is necessary to send the maps, two weeks before the exam date, to the course instructor, who will verify their compliance with the university guidelines and may request modifications.

    Additional Information for Non-Attending Students

    Attendance

    Identical to that of attending students.

    Course books

    Identical to that of attending students.

    Assessment

    Identical to that of attending students.

    Disability and Specific Learning Disorders (SLD)

    Students who have registered their disability certification or SLD certification with the Inclusion and Right to Study Office can request to use conceptual maps (for keywords) during exams.

    To this end, it is necessary to send the maps, two weeks before the exam date, to the course instructor, who will verify their compliance with the university guidelines and may request modifications.

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