Università degli Studi di Urbino Carlo Bo / Portale Web di Ateneo


Struttura
Dipartimento di Scienze Biomolecolari (DISB) Urbino Piazza Rinascimento, 6 0722 303333 simone.lucarini@uniurb.it
Sito web

During his scientific activity, Prof. Lucarini carried out research in the fields of Medicinal, Supramolecular, and Organic Chemistry in order to obtain new original methods for obtaining achiral and chiral molecules of pharmaceutical-biological interest, together with the development of new synthetic methods of potential industrial interest. In detail, during his undergrad thesis (Bologna), he did research in the field of foldamers, new oligomers with predictable three-dimensional structures with high biological activity. During his doctoral thesis (Urbino and Kansas, USA), he worked on the design, synthesis, and study of the anionic and cationic binding properties of new macrocycles for biological applications such as imaging for medical diagnostics. He then started working on the design and synthesis of diastero- and enantioselective ligands for melatonergic receptors. During the post-doc period in Tokyo (Japan), coinciding with the "avian pandemic", he developed a new synthetic method that is plausibly applicable to the production of (-) - shikimic acid, a key intermediate for the synthesis of Tamiflu, starting from achiral reagents and readily available on the market. Then, he developed new methodologies for the synthesis of natural products, containing the indole nucleus, with potential antitumor activity. Recently, he started a new and promising research line concerning the design and synthesis of new glycolipid for pharmaceutical/medicinal applications. In the last couple of years, he has been expanding the biological application of bisindoles, and in particular to the treatment of Leishmaniasis.

55) Mattia Tiboni, Enas Elmowafy, Marwa O. El-Derany, Serena Benedetti, Raffaella Campana, Michele Verboni, Lucia Potenza, Francesco Palma, Barbara Citterio, Maurizio Sisti, Andrea Duranti, Simone Lucarini, Mahmoud E. Soliman and Luca Casettari; Int. J. Pharmaceut. 2022, 616, 121508; “A combination of sugar esters and chitosan to promote in vivo wound care”. IF = 6.510, Q1 in Pharmacology & Pharmacy (2021)

54) Aurora Diotallevi, Laura Scalvini, Gloria Buffi, Yolanda Pérez-Pertejo, Mauro De Santi, Michele Verboni, Gianfranco Favi, Mauro Magnani, Alessio Lodola, Simone Lucarini* and Luca Galluzzi; ACS Omega 2021, 6 (51), 35699; “Phenotype Screening of an Azole-bisindole Chemical Library Identifies URB1483 as a New Antileishmanial Agent Devoid of Toxicity on Human Cells”. IF = 4.132, Q2 in Multidisciplinary Chemistry

53) Michele Verboni, Simone Lucarini* and Andrea Duranti; Pharmaceuticals 2021, 14 (12), 1306; “6’-O-Lactose Ester Surfactants as an Innovative Opportunity in the Pharmaceutical Field: from Synthetic Methods to Biological Applications”. IF = 5.215, Q2 in Medicinal Chemistry

52) Franks Kamgang Nzekouea, Marco Agostini, Michele Verboni, Caterina Renzoni, Lucia Alfieri, Simone Barocci, Massimo Ricciutelli, Giovanni Caprioli and Simone Lucarini; J. Pharm. Biomed. Anal. 2021, 205, 114310; “A comprehensive UHPLC–MS/MS screening method for the analysis of 98 New Psychoactive Substances and related compounds in human hair”. IF = 3.571, Q2 in Pharmacology & Pharmacy

51) Fiona McCartney, Diego R. Perinelli, Mattia Tiboni, Robert Cavanagh, Simone Lucarini, Giovanni Filippo Palmieri, Luca Casettari and David J. Brayden; Int. J. Pharmaceut. 2021, 601, 120593; “Permeability-enhancing effects of three laurate-disaccharide monoesters across isolated rat intestinal mucosae”. IF = 6.510, Q1 in Pharmacology & Pharmacy

Prodotti della Ricerca di Simone Lucarini.

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Insegnamento
Course
2024/2025 ANALISI DEI FARMACI QUANTITATIVA CON LABORATORIO
QUANTITATIVE DRUG ANALYSIS AND LABORATORY
2024/2025 PRODOTTI NATURALI IN CHIMICA FARMACEUTICA
NATURAL PRODUCTS IN MEDICINAL CHEMISTRY
2024/2025 PRODOTTI NATURALI IN CHIMICA FARMACEUTICA
NATURAL PRODUCTS IN MEDICINAL CHEMISTRY
mutuato
2024/2025 PRODOTTI NATURALI IN CHIMICA FARMACEUTICA
NATURAL PRODUCTS IN MEDICINAL CHEMISTRY
mutuato
2024/2025 PRODOTTI NATURALI IN CHIMICA FARMACEUTICA
NATURAL PRODUCTS IN MEDICINAL CHEMISTRY
mutuato
2023/2024 ANALISI DEI MEDICINALI I
Drug Analysis I
Course with optional materials in a foreign language
2023/2024 PRODOTTI NATURALI IN CHIMICA FARMACEUTICA
NATURAL PRODUCTS IN MEDICINAL CHEMISTRY
Course with optional materials in a foreign language
2023/2024 PRODOTTI NATURALI IN CHIMICA FARMACEUTICA
NATURAL PRODUCTS IN MEDICINAL CHEMISTRY
mutuato
Course with optional materials in a foreign language
2023/2024 PRODOTTI NATURALI IN CHIMICA FARMACEUTICA
NATURAL PRODUCTS IN MEDICINAL CHEMISTRY
mutuato
Course with optional materials in a foreign language
2023/2024 PRODOTTI NATURALI IN CHIMICA FARMACEUTICA
NATURAL PRODUCTS IN MEDICINAL CHEMISTRY
mutuato
Course with optional materials in a foreign language
2023/2024 QUANTITATIVE AND QUALITATIVE METHODOLOGIES IN CHEMICAL RESEARCH (MOD. 2)
QUANTITATIVE AND QUALITATIVE METHODOLOGIES IN CHEMICAL RESEARCH (MOD. 2)
Course entirely taught in a foreign language
2022/2023 ANALISI DEI MEDICINALI I
Drug Analysis I
Course with optional materials in a foreign language
2022/2023 MOLECULAR STRUCTURE DETERMINATION
MOLECULAR STRUCTURE DETERMINATION
Course entirely taught in a foreign language
2022/2023 PRODOTTI NATURALI IN CHIMICA FARMACEUTICA
NATURAL PRODUCTS IN MEDICINAL CHEMISTRY
Course with optional materials in a foreign language
2022/2023 PRODOTTI NATURALI IN CHIMICA FARMACEUTICA
NATURAL PRODUCTS IN MEDICINAL CHEMISTRY
mutuato
Course with optional materials in a foreign language
2022/2023 PRODOTTI NATURALI IN CHIMICA FARMACEUTICA
NATURAL PRODUCTS IN MEDICINAL CHEMISTRY
mutuato
Course with optional materials in a foreign language
2021/2022 ANALISI DEI MEDICINALI I
Drug Analysis I
Course with optional materials in a foreign language
2021/2022 MOLECULAR STRUCTURE DETERMINATION
MOLECULAR STRUCTURE DETERMINATION
Course entirely taught in a foreign language
2021/2022 PRODOTTI NATURALI IN CHIMICA FARMACEUTICA
NATURAL PRODUCTS IN MEDICINAL CHEMISTRY
Course with optional materials in a foreign language
2021/2022 PRODOTTI NATURALI IN CHIMICA FARMACEUTICA
NATURAL PRODUCTS IN MEDICINAL CHEMISTRY
mutuato
2021/2022 PRODOTTI NATURALI IN CHIMICA FARMACEUTICA
NATURAL PRODUCTS IN MEDICINAL CHEMISTRY
mutuato
2020/2021 ANALISI DEI MEDICINALI I
Drug Analysis I
Course with optional materials in a foreign language
2019/2020 ANALISI DEI MEDICINALI I
Drug Analysis I
Course with optional materials in a foreign language
2018/2019 ANALISI DEI MEDICINALI I
Drug Analysis I
Course with optional materials in a foreign language
2018/2019 ANALISI DEI MEDICINALI II
Drug Analysis II
Course with optional materials in a foreign language
2017/2018 ANALISI DEI MEDICINALI II
Drug Analysis II
Course with optional materials in a foreign language
2016/2017 ANALISI DEI MEDICINALI II
Drug Analysis II
Course with optional materials in a foreign language
2015/2016 ANALISI DEI MEDICINALI II
Drug Analysis II
2014/2015 Analisi dei medicinali II
2013/2014 Analisi dei medicinali II
2012/2013 Analisi dei medicinali II
2011/2012 Analisi dei medicinali I
2010/2011 Analisi dei medicinali I
2009/2010 Analisi dei medicinali I
2008/2009 Analisi dei medicinali I
Giorno Orario Attività Aula

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